
NNI Workshop
This Medline/PubMed indexed series contains the full proceedings of the Nestlé Nutrition Institute Workshop series
Here you will find freely downloadable publications on the latest nutrition topics, such as early infant nutrition, nutritional avenues to allergies, sports nutrition, and nutrition in disease states such as dysphagia or critical illness. All 3000 papers are organized across categories to make it easier for you to find specific information. If you are missing a reference you can also use our search function.
Sponsorship Disclosure: Many of the publications, programs, conferences, educational resources and other content available on this website have been funded and/or prepared by the Nestle Nutrition Institute or its Nestle affiliates.
Infant feeding is a large component of parenting that encompasses the social, cultural, and economic structure of a parent’s life. There are universal challenges for parents, no matter where in the world they are raising their children. Health Care Professionals are the preferred source on parenting advice. Their role in education and support is key to empower parents to adopt recommended infant feeding.
Prevention of allergic disease in children has been on the agenda for many decades. Although several studies have been performed in the last 3 decades with both types of hydrolyzed formulae (extensively and partially hydrolyzed) with regard to their ability to prevent allergic diseases, the most important findings derive from the German Infant Nutritional Intervention study (GINI). The GINI study is by far the largest study in the field of allergy prevention with hydrolysates and the study with the longest follow-up (up to now until 20 years). The findings confirm the concept that early nutritional intervention with certain hydrolyzed formulae, if exclusive breastfeeding is not feasible, has a preventive effect until adulthood for both eczema and allergic airway manifestation.
This is a conference proceedings from the symposium that took place on 16th October 2020 at Food Allergy and Anaphylaxis Meeting and the European Consortium on Application of Flow Cytometry in Allergy (FAAM-EUROBAT) Digital 2020. This symposium was designed to provide an update on recent advances in our understanding of the role of human milk oligosaccharides (HMO) in the management of infant food allergies, specifically cow’s milk protein allergy (CMPA).
Food allergies affect around 240-550 million people worldwide. They are most common in infants and children. While in most cases, food allergies cause mild symptoms, some can cause severe reactions, and may even be life-threatening.
Mild cognitive impairment (MCI) refers to a transitional stage between normal aging and dementia. MCI is defined by an objective decline in cognitive functioning (using appropriate cognitive tests) that exceeds the expected level given the patient’s age and education. Such cognitive changes do not impair social functioning or activities of daily living.
Vitamin D is a prohormone absorbed from food sources or supplements and also synthesized in the skin following exposure to ultraviolet light. Few foods naturally contain vitamin D.
Around half of Filipino children 1-5 years old are not consuming any dairy products on a given day, which increases risk of inadequate nutrient intakes. Dietary modelling was applied to assess the nutritional impact of meeting dairy recommendations in reducing nutrient inadequacy. If all children would meet their dairy recommendations, theoretical reductions in population nutrient inadequacy would be seen for all micronutrients. Therefore, dairy consumption should be encouraged.
Milk and rice were the main dietary components in all Filipino children, contributing up to 60% of energy in the infants from poorer households. Consumption of protein-containing foods and vegetables were typically lower in poorer households. Interventions are required to enable caregivers of young Filipino children to provide complementary foods of high nutritional quality, particularly among children from the poor households.
Human milk oligosaccharides (HMOs) vary among mothers and genetic factors contribute to this variability. This study assessed changes in HMO concentrations during the first year of lactation and the relationship with FUT2 Secretor group and FUT3 Lewis group defining genetic polymorphisms.
Breastfeeding is thought to be protective against Atopic Dermatitis (AD) and Food Allergy (FA), but the data are controversial, and mechanisms are not well understood.
Functional gastrointestinal disorders (FGIDs) often lead to referral to a paediatrician during the first 6 months of life and are often responsible for hospitalisation, feeding changes, use of drugs, parental anxiety, and loss of parental working days with relevant social consequences. “Current evidence suggests that L reuteri may be effective in the prevention of some functional gastrointestinal disorders, such as colic and regurgitation. Preliminary data also suggest that L reuteri may be useful for treating functional constipation.”
Gastrointestinal woes – such as gastroesophageal reflux, colic and dyschezia – are common among infants. “Gastrointestinal woes are common among infants. Many of these resolve spontaneously and do not need extensive testing or treatment.”
The evidence base supporting the use of pHF in primary allergy prevention continues to evolve. When reviewing available literature, it is important to note that the ability to draw conclusions largely depends on the study design. “The protein source, the degree of hydrolysis and the processing techniques used in the manufacture of hydrolysed formula differ across companies and accounts for the differences between formula’s ability to confer allergy preventive effects.”
A 2017 meta-analysis concluded that the use of pHF reduces the risk of eczema and all allergic diseases at some, albeit not all, time points among children at high risk for allergy. “…not all hydrolysed formulas are the same; when considering a hydrolysed formula for allergy prevention, it is vital to choose one that has been proven or confirmed to have reduced allergenicity.”
The world’s population is ageing. According to data from the World Population Prospects: the 2019 Revision, by 2050, one in six people in the world will be over age 65 (16%), up from one in 11 in 2019 (6%).
According to the World Health Organization, the early child period, i.e., from birth to 5 years of age, is considered the most important developmental phase throughout the lifespan.
The following paper investigated three variations of the balanced carbohydrate ratio and its ability to identify products of a higher nutritional quality in products from Australia, Malaysia, Singapore, Thailand and the Philippines.
Carbohydrate quality is critical for health, nevertheless validated and pragmatic metrics to define the quality of carbohydrate-rich products are not established. This paper investigated four different carbohydrate metrics based on the ratio between total carbohydrate and fibre and/or free sugars.
Dietary fibre and its associated non-carbohydrate components have been inversely associated with disease outcomes.
Dietary guidelines indicate that complex carbohydrates should provide around half of the calories in a balanced diet, while sugars (i.e. simple carbohydrates) should be limited to no more than 5–10% of total energy intake.