This Medline/PubMed indexed series contains the full proceedings of the Nestlé Nutrition Institute Workshop series in Pediatric, Clinical, Adult and Sports Nutrition.
A series of pediatric health and nutrition journals comprising up-to-date reviews on hot topics. The Annales are published as a supplement to the Annals of Nutrition and Metabolism and indexed in Medline/PubMed.
Concise, science-based up-to-date practical information for health professionals in key areas of pediatric health and nutrition.
A collection of journal articles from leading nutrition publications available free of charge to NNI member.
Proceedings of international conferences covering hot topics in nutrition and special scientific highlights.
Growth and Metabolic Outcomes in Healthy Infants Fed Formulas with Age-Adapted Protein Concentrations from Birth Through 12 Months
Human milk composition changes dynamically during lactation, whereas infant formula composition is relatively static. This may contribute to growth/metabolic differences between breastfed and formula-fed infants. The aim of this study was to evaluate growth and metabolic outcomes in healthy term infants fed sequential formulas with age-adapted protein concentrations from birth to 12 months, in comparison to breastfed infants.
Starter and Follow-up Formula with a Specific Blend of Five Human Milk Oligosaccharides Support Age-Appropriate Growth, are Safe and Suitable
Breastmilk is abundant in structurally diverse HMOs. Scientific evidence shows HMOs have different biological functions important for a healthy development in early life. New research presents 12-month follow-up data from a study evaluating infant and follow-up formula containing a blend of 5 different HMOs, designed to represent some of the major HMOs found in breastmilk.
In the first published clinical trial using an innovative device to measure glycemic response to different feeding regimens in healthy infants, reports a lower-protein follow-on formula with 100% lactose complemented with infant cereal with whole grain and pulses promoted lower glycemic response along with lower insulin demand and less insulin secretion, which may have beneficial long-term effects on metabolic health.
Safety and efficacy of a probiotic-containing infant formula supplemented with 2’-fucosyllactose: a double-blind randomized controlled trial
Human milk oligosaccharides (HMOs) have important and diverse biological functions in early life. This study tested the safety and efficacy of a starter infant formula containing Limosilactobacillus (L.) reuteri DSM 17938 and supplemented with 2’‑fucosyllactose (2’FL).
Effects of an Extensively Hydrolyzed Formula Supplemented with Two Human Milk Oligosaccharides on Growth, Tolerability, Safety and Infection Risk in Infants with Cow’s Milk Protein Allergy: A Randomized, Multi-Center Trial
This randomized clinical trial (Registration: NCT03085134) assessed if an extensively hydrolyzed formula (EHF) supplemented with two human milk oligosaccharides (HMO) and reduced protein content (2.20 g/100 kcal) supports normal growth in infants with cow’s milk protein allergy (CMPA).
Human Milk Oligosaccharide-Stimulated Bifidobacterium Species Contribute to Prevent Later Respiratory Tract Infections
Human milk oligosaccharides (HMOs) may support immune protection, partly via their action on the early-life gut microbiota. Exploratory findings of a randomized placebo- controlled trial associated 2′fucosyllactose (2′FL) and lacto-N-neotetraose (LNnT) formula feeding with reduced risk for reported bronchitis and lower respiratory tract illnesses (LRTI), as well as changes in gut microbiota composition.
Human milk oligosaccharides (HMOs) have been researched by scientists for over 100 years, driven by the substantial evidence for the nutritional and health benefits of mother's milk. Yet research has truly bloomed during the last decade, thanks to progress in biotechnology, which has allowed the production of large amounts of bona fide HMOs.
Over the last few years, published reports document the presence of heavy metals in certain foods. This is of particular concern when these foods are consumed by infants and young children due to the potential effect of heavy metal exposure on neurological development even at low levels.
The growing global prevalence of allergy, particularly among children, poses a major public health problem and multipronged approaches for allergy prevention are under active investigation, focusing on key periods during pregnancy and early infancy.
While the gut microbiota was once called “the forgotten organ”, it is no longer forgotten. On the contrary, it is a hot topic for research, as documented by the rapidly increasing number of scientific papers on this subject as well as coverage in the lay press,
The Clinical and Therapeutic Implications of Meal Replacements: Sustained Weight Loss for Improved Liver Health and Diabetes Remission
Type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD), which includes non-alcoholic steatohepatitis (NASH), are highly prevalent diseases associated with an increased risk of morbidity and mortality. Obesity/overweight and dietary intake are important risk factors.
Postprandial Glycaemic Excursions: Implications for Health and Effects of Nonpharmacological Interventions” – Proceedings from NNI Symposium at 2021 Virtual EASD Annual Meeting
The Ominous Quartet’ represents four glycaemic disorders at the centre of cardiovascular diseases in diabetes, including ambient hyperglycaemia, glycaemic variability (GV), postprandial glucose (PPG) excursions, and hypoglycaemic episodes. It is important to understand the interrelationship between these disorders, targets and thresholds for monitoring purposes, and impact on cardiovascular outcomes.
The first nutrient reference framework for plant-based beverages (PBB) has been published with the aim to guide the development and formulation of healthy plant-based beverages of high nutritional quality. Often viewed as equivalent to milk in nutritional value, many PBB are often low in protein and are fortified with varying amounts of calcium, and vitamins A and D.
The Influence of FUT2 and FUT3 Polymorphisms and Nasopharyngeal Microbiome on Respiratory Infections in Breastfed Bangladeshi Infants from the Microbiota and Health Study
Acute respiratory infections (ARI) are one of the most common causes of morbidity and mortality in young children. By studying 240 Bangladeshi mother-infant pairs, it was observed that, while the community of microbes present in the nasopharynges of infants was not associated with later onset of ARI, maternal genetic polymorphisms on a gene involved in shaping the composition of human breast milk influences the occurrence of ARIs.
In collaboration with the University of Leipzig, Nestlé Research explored the association of Human Milk Oligosaccharides (HMOs) in the breast milk of 143 mothers with maternal and infant parameters including infant and child growth from 3 months to 7 years of age.
Visceral or intra-organ fat (VIF) accumulation may be a better indication of cardiovascular and metabolic disease risk than BMI. The link with increased disease risk may be through dysfunctional adiposity, leading to excess ectopic fat deposition and hence inflammatory and adipokine dysregulation, insulin resistance, and atherogenic dyslipidaemia.
It has become increasingly more evident during Covid-19 pandemic times that nutrition plays a significant role for the healthy development of the child, starting already from pregnancy.
The year 2020 has been a year where a new virus, SARS-CoV-2, changed the world. With that, the food chain was challenged in many parts of the world. Ensuring adequate nutrition to secure the growth and well-being, particularly of infants and young children, met new obstacles.
Milk intake during childhood and adolescence, adult bone density, and osteoporotic fractures in US women
Adequate calcium intake is critical in school-age years to ensure adequate bone mineralisation; however, the effects of adequacy in childhood on bone health in later years is not well documented. In this study, researchers sought to determine whether milk intake during childhood and adolescence is associated with adult bone mass (bone mineral content), bone mineral density, and the incidence of osteoporotic fracture.
Food literacy is a promising approach to support healthy dietary behaviours in adolescents. However, adolescents' perspectives on food literacy and the impact it could have on their dietary behaviours are not well understood. This study explored adolescents' perspectives on the potential for food literacy to influence their dietary behaviours.