HMO Academy

Human Milk Oligosaccharides (HMOs) are complex sugars that are available in human milk. They are the 3rd largest solid component in breast milk after fat and lactose and have no nutritive function. HMOs are responsible for directly stimulating the immune system by promoting good gut bacteria, strengthening the gut barrier function and blocking pathogens.

Human Milk Oligosaccharides are an exciting and central area of research in infant nutrition. Scientific advances on HMOs are helping us know more about the role and importance of these essential components of Human milk. The HMO Academy has been created to share evidence-based information in interactive and user-friendly way from more than a decade of research on HMOs.

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The Nest

The Nest 40: Human Milk Oligosaccharides

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From Basic Science to Clinical Implication: The HMO Story So Far

Abstract Brochure

Human Milk Oligosaccharides support immune protection

Abstract Brochure

Nestlé Research on Human Milk Oligosaccharides: Latest Update

Article

HMOs: New Ways to Shape the Gut Microbiome in CMPA

The Nest

The Nest 44: Pro-, Pre-, and Synbiotics: Myths and Facts

Abstract Brochure

Human Milk Oligosaccharides: Where Do We Go from Here?

NNIW Brochure

NNIW88 Brochure: Intestinal Microbiome: Functional Aspects in Health & Disease

NNIW Brochure

NNIW90 Brochure: Human Milk: Composition, Clinical Benefits and Future Opportunities

Article

First clinical study to report on the effects of supplementation with 2 HMOs

Article

Human Milk Oligosaccharides: the Link between Mother’s and Baby’s Health

Article

2’fucosyllactose is well tolerated in a partially hydrolyzed Whey Protein

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Benefits of two Human Milk Oligosaccharides, 2FL and LNnT in Infant Nutrition

Videos >

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Library >

The Nest 40: Human Milk Oligosaccharides

From Basic Science to Clinical Implication: The HMO Story So Far

Human Milk Oligosaccharides support immune protection

Nestlé Research on Human Milk Oligosaccharides: Latest Update

HMOs: New Ways to Shape the Gut Microbiome in CMPA

The Nest 44: Pro-, Pre-, and Synbiotics: Myths and Facts

Human Milk Oligosaccharides: Where Do We Go from Here?

NNIW88 Brochure: Intestinal Microbiome: Functional Aspects in Health & Disease

NNIW90 Brochure: Human Milk: Composition, Clinical Benefits and Future Opportunities

First clinical study to report on the effects of supplementation with 2 HMOs

Human Milk Oligosaccharides: the Link between Mother’s and Baby’s Health

2’fucosyllactose is well tolerated in a partially hydrolyzed Whey Protein

Benefits of two Human Milk Oligosaccharides, 2FL and LNnT in Infant Nutrition

Videos >

Yvan Vandenplas: How HMOs Boost Immunity

Carine Blanchard: HMOs and allergic sensitization: current evidence

Lars Bode: The Science of HMO's what they are and what they do

Sagar Thakkar: Lactation for infant feeding expertise (LIFE) focus on HMO's

Ryan Carvalho: Learnings from the last decade of clinical evidence on HMOs

Philippe Alliet: Term Infant Formula Supplemented with 2’FL Reduces the Abundance of Pathogenic Bacteria during Early Infancy

Aristea Binea: HMO levels in breast milk do not correlate or predict infant growth

Jane Natividad: Human Milk Oligosaccharides Confer Resistance against Inflammation-mediated Intestinal Epithelial Barrier Dysfunction

Jane Natividad: Microbial Products Derived From HMO Fermentation by Infant Microbiota Protect Against Inflammation

Jonas Hauser: Early Life Presence of 6’SL Alters Microbiota

Jonas Hauser: Sialylated HMOs are Shaping the Development of Cognitive Functions

Jonas Hauser: Early Life Supplementation with Blends of (HMO) Improves Cognitive Functions

Weili Lin: A Positive Correlation between Breast Milk 3’ Sialyllactose and Language Development

Jonas Hauser: Glutamatergic Gene Expression Mediates the Relationship between Gut Bacteria

Sharon Donovan: Human Milk Oligosaccharides and Neonatal Immunity

Hania Szajewska: Evidence-based Medicine and HMOs

Norbert Sprenger: Human milk oligosaccharides factors

Lars Bode: Human Milk Oligosaccharides: next Generation Functions and Questions

Philippe Alliet: Clinical Studies: what is known and what needs further Studies?

Yvan Vandenplas: HMOs story so far

Seppo Salminen: Human Milk Oligosaccharides: regulatory Aspects

Lars Bode: Milk Oligosaccharides structure and function

Clemens Kunz: HMOs: just a Sugar or Nature’s secret Weapon

Norbert Sprenger: HMO – physiological Significance

Continuous Medical Education >

Module 1: Human Milk Oligosaccharides: Basic Science and Physiological Significance

Module 2: Effects of Human Milk Oligosaccharides on Gut Microbiota and beyond

Module 3: Role of Human Milk Oligosaccharides in the Protection against Infections and Necrotising Enterocolitis

Module 4: Human Milk Oligosaccharides: Complex structure and Specific Functional Benefits

Module 5 Human Milk Oligosaccharides: Clinical Evidence

New findings on HMO research

Practical Resources >

Human Milk Oligosaccharides: A Child's Health Guardian

Human Milk Oligosaccharides: Help Strengthen an Infant's Immunity

What are HMOs: basic science

The benefits of Human Milk Oligosaccharides on immunity

Human Milk Oligosaccharides (structure and functions)

2’fucosyllactose is well tolerated in a partially hydrolysed Whey Protein Infant Formula with a probiotic

HMOs: clinical studies

Effects of Infant Formula with HMOs on Growth and Morbidity

Infants fed a Formula containing 2’FL have lower inflammatory Cytokines

How do HMOs support babies immunity

Addition of 2’FL brings Infant Formulae closer to Human Milk

Innate Protection conferred by fucosylated Oligosaccharides

What makes HMOs unique?

Do HMOs have a protective role in reducing the risk of respitory infections

News >

Content of HMO 2FL in breast milk is associated with higher cognitive development scores at 2 years

Human Milk Oligosaccharides may play a role in Childhood Obesity Prevention?

HMOs in Infant Formula – Latest Research Reviewed

Immunological Effects of Human Milk Oligosaccharides: New Scientific Review

HMO, 6’Sialyllactose in early Life plays a key Role in the Brain Development of Mice

Role of 2′-fucosylated HMOs in the Reduction of respiratory Infections in Babies

HMOs stimulate Bifidobacteria that contribute to reduce the Risk of lower Respiratory Tract Illnesses

HMOs, 6’SL, in pre-weaning Milk modulates Microbiota Composition and improves adult Cognitive Functions

HMOs, 3′SL, in pre-weaning Milk influences Attention, Learning and Memory later in Life