HMO Academy

Human Milk Oligosaccharides (HMOs) are complex sugars that are available in human milk. They are the 3rd largest solid component in breast milk after fat and lactose and have no nutritive function. HMOs are responsible for directly stimulating the immune system by promoting good gut bacteria, strengthening the gut barrier function and blocking pathogens.

Human Milk Oligosaccharides are an exciting and central area of research in infant nutrition. Scientific advances on HMOs are helping us know more about the role and importance of these essential components of Human milk. The HMO Academy has been created to share evidence-based information in interactive and user-friendly way from more than a decade of research on HMOs.

Library >
Avatar
The Nest
The Nest 40: Human Milk Oligosaccharides
Avatar
Abstract Brochure
From Basic Science to Clinical Implication: The HMO Story So Far
Avatar
Abstract Brochure
Human Milk Oligosaccharides support immune protection
Avatar
Abstract Brochure
Nestlé Research on Human Milk Oligosaccharides: Latest Update
Avatar
Article
HMOs: New Ways to Shape the Gut Microbiome in CMPA
Avatar
The Nest
The Nest 44: Pro-, Pre-, and Synbiotics: Myths and Facts
Avatar
Abstract Brochure
Human Milk Oligosaccharides: Where Do We Go from Here?
Avatar
NNIW Brochure
NNIW88 Brochure: Intestinal Microbiome: Functional Aspects in Health & Disease
Avatar
NNIW Brochure
NNIW90 Brochure: Human Milk: Composition, Clinical Benefits and Future Opportunities
Avatar
Article
First clinical study to report on the effects of supplementation with 2 HMOs
Avatar
Article
Human Milk Oligosaccharides: the Link between Mother’s and Baby’s Health
Avatar
Article
2’fucosyllactose is well tolerated in a partially hydrolyzed Whey Protein
Avatar
Article
Benefits of two Human Milk Oligosaccharides, 2FL and LNnT in Infant Nutrition
Videos >
Avatar
Video Teaser
Yvan Vandenplas: How HMOs Boost Immunity
Avatar
Video
Viktor Bauer: Term infant formula supplemented with a unique blend of 5 HMOs
Florence Rochat: Impact of HMO on toddler microbiota and its activity
Video
Florence Rochat: Impact of HMO on toddler microbiota and its activity
Lars Bode: The Science of HMO's what they are and what they do
Video Teaser
Lars Bode: The Science of HMO's what they are and what they do
Sagar Thakkar: Lactation for infant feeding expertise (LIFE) focus on HMO's
Video Teaser
Sagar Thakkar: Lactation for infant feeding expertise (LIFE) focus on HMO's
Ryan Carvalho: Learnings from the last decade of clinical evidence on HMOs
Video Teaser
Ryan Carvalho: Learnings from the last decade of clinical evidence on HMOs
Philippe Alliet: Term Infant Formula Supplemented with 2’FL Reduces the Abundance of Pathogenic Bacteria during Early Infancy
Video
Philippe Alliet: Term Infant Formula Supplemented with 2’FL Reduces the Abundance of Pathogenic Bacteria during Early Infancy
HMO diversity impacts infant microbiota activity
Video
Florence Rochat: HMO diversity impacts infant microbiota activity
Aristea Binea: HMO levels in breast milk do not correlate or predict infant growth
Video
Aristea Binea: HMO levels in breast milk do not correlate or predict infant growth
Carine Blanchard: HMOs and allergic sensitization: current evidence
Video Teaser
Carine Blanchard: HMOs and allergic sensitization: current evidence
Jane Natividad: Human Milk Oligosaccharides Confer Resistance against Inflammation-mediated Intestinal Epithelial Barrier Dysfunction
Video
Jane Natividad: Human Milk Oligosaccharides Confer Resistance against Inflammation-mediated Intestinal Epithelial Barrier Dysfunction
Jane Natividad: Microbial Products Derived From HMO Fermentation by Infant Microbiota Protect Against Inflammation
Video
Jane Natividad: Microbial Products Derived From HMO Fermentation by Infant Microbiota Protect Against Inflammation
Jonas Hauser: Early Life Presence of 6’SL Alters Microbiota
Video
Jonas Hauser: Early Life Presence of 6’SL Alters Microbiota
Jonas Hauser: Sialylated HMOs are Shaping the Development of Cognitive Functions
Video
Jonas Hauser: Sialylated HMOs are Shaping the Development of Cognitive Functions
Jonas Hauser: Early Life Supplementation with Blends of (HMO) Improves Cognitive Functions
Video
Jonas Hauser: Early Life Supplementation with Blends of (HMO) Improves Cognitive Functions
Weili Lin: A Positive Correlation between Breast Milk 3’ Sialyllactose and Language Development
Video
Weili Lin: A Positive Correlation between Breast Milk 3’ Sialyllactose and Language Development
Jonas Hauser: Glutamatergic Gene Expression Mediates the Relationship between Gut Bacteria
Video
Jonas Hauser: Glutamatergic Gene Expression Mediates the Relationship between Gut Bacteria
Sharon Donovan: Human Milk Oligosaccharides and Neonatal Immunity
Video Teaser
Sharon Donovan: Human Milk Oligosaccharides and Neonatal Immunity
Hania Szajewska: Evidence-based Medicine and HMOs
Video Teaser
Hania Szajewska: Evidence-based Medicine and HMOs
Norbert Sprenger: Human milk oligosaccharides factors
Expert Interview
Norbert Sprenger: Human milk oligosaccharides factors
Lars Bode: Human Milk Oligosaccharides: next Generation Functions and Questions
Video Teaser
Lars Bode: Human Milk Oligosaccharides: next Generation Functions and Questions
Philippe Alliet: Clinical Studies: what is known and what needs further Studies?
Video Teaser
Philippe Alliet: Clinical Studies: what is known and what needs further Studies?
Yvan Vandenplas: HMOs story so far
Video Teaser
Yvan Vandenplas: HMOs story so far
Seppo Salminen: Human Milk Oligosaccharides: regulatory Aspects
Video Teaser
Seppo Salminen: Human Milk Oligosaccharides: regulatory Aspects
Lars Bode: Milk Oligosaccharides structure and function
Expert Interview
Lars Bode: Milk Oligosaccharides structure and function
Clemens Kunz: HMOs: just a Sugar or Nature’s secret Weapon
Video Teaser
Clemens Kunz: HMOs: just a Sugar or Nature’s secret Weapon
Norbert Sprenger: HMO – physiological Significance
Video Teaser
Norbert Sprenger: HMO – physiological Significance
Continuous Medical Education >
Module 1: Human Milk Oligosaccharides: Basic Science and Physiological Significance
Tutorial
Module 1: Human Milk Oligosaccharides: Basic Science and Physiological Significance
Module 2: Effects of Human Milk Oligosaccharides on Gut Microbiota and beyond
Tutorial
Module 2: Effects of Human Milk Oligosaccharides on Gut Microbiota and beyond
Module 3: Role of Human Milk Oligosaccharides in the Protection against Infections and Necrotising Enterocolitis
Tutorial
Module 3: Role of Human Milk Oligosaccharides in the Protection against Infections and Necrotising Enterocolitis
Module 4: Human Milk Oligosaccharides: Complex structure and Specific Functional Benefits
Tutorial
Module 4: Human Milk Oligosaccharides: Complex structure and Specific Functional Benefits
Module 5 Human Milk Oligosaccharides: Clinical Evidence
Tutorial
Module 5 Human Milk Oligosaccharides: Clinical Evidence
New findings on HMO research
Tutorial
New findings on HMO research
Practical Resources >
how can preterm infants benefit from human milk oligosaccharides landscape.png
Infographic
How Can Preterm Infants Benefit From Human Milk Oligosaccharides
Human Milk Oligosaccharides: A Child's Health Guardian
Infographic
Human Milk Oligosaccharides: A Child's Health Guardian
Human Milk Oligosaccharides: Help Strengthen an Infant's Immunity
Infographic
Human Milk Oligosaccharides: Help Strengthen an Infant's Immunity
role of HMOs slide deck preview
Presentation Slides
Role of HMOs in Preterm Nutrition
What are HMOs: basic science
Presentation Slides
What are HMOs: basic science
the benefits of HMOs on immunity.png
Infographic
The benefits of Human Milk Oligosaccharides on immunity
Human Milk Oligosaccharides (structure and functions)
Infographic
Human Milk Oligosaccharides (structure and functions)
2’fucosyllactose is well tolerated in a partially hydrolysed Whey Protein Infant Formula with a probiotic
Publication Digest
2’fucosyllactose is well tolerated in a partially hydrolysed Whey Protein Infant Formula with a probiotic
HMOs: clinical studies
Presentation Slides
HMOs: clinical studies
Effects of Infant Formula with HMOs on Growth and Morbidity
Publication Digest
Effects of Infant Formula with HMOs on Growth and Morbidity
Infants fed a Formula containing 2’FL have lower inflammatory Cytokines
Publication Digest
Infants fed a Formula containing 2’FL have lower inflammatory Cytokines
How do HMOs support babies immunity
Fast Facts
How do HMOs support babies immunity
Addition of 2’FL brings Infant Formulae closer to Human Milk
Publication Digest
Addition of 2’FL brings Infant Formulae closer to Human Milk
Innate Protection conferred by fucosylated Oligosaccharides
Publication Digest
Innate Protection conferred by fucosylated Oligosaccharides
What makes HMOs unique?
Fast Facts
What makes HMOs unique?
Do HMOs have a protective role in reducing the risk of respitory infections
Fast Facts
Do HMOs have a protective role in reducing the risk of respitory infections
News >
Content of HMO 2FL in breast milk is associated with higher cognitive development scores at 2 years
News
Content of HMO 2FL in breast milk is associated with higher cognitive development scores at 2 years
Human Milk Oligosaccharides may play a role in Childhood Obesity Prevention?
News
Human Milk Oligosaccharides may play a role in Childhood Obesity Prevention?
HMOs in Infant Formula – Latest Research Reviewed
News
HMOs in Infant Formula – Latest Research Reviewed
Immunological Effects of Human Milk Oligosaccharides: New Scientific Review
News
Immunological Effects of Human Milk Oligosaccharides: New Scientific Review
HMO, 6’Sialyllactose in early Life plays a key Role in the Brain Development of Mice
News
HMO, 6’Sialyllactose in early Life plays a key Role in the Brain Development of Mice
Role of 2′-fucosylated HMOs in the Reduction of respiratory Infections in Babies
News
Role of 2′-fucosylated HMOs in the Reduction of respiratory Infections in Babies
HMOs stimulate Bifidobacteria that contribute to reduce the Risk of lower Respiratory Tract Illnesses
News
HMOs stimulate Bifidobacteria that contribute to reduce the Risk of lower Respiratory Tract Illnesses
HMOs, 6’SL, in pre-weaning Milk modulates Microbiota Composition and improves adult Cognitive Functions
News
HMOs, 6’SL, in pre-weaning Milk modulates Microbiota Composition and improves adult Cognitive Functions
HMOs, 3′SL, in pre-weaning Milk influences Attention, Learning and Memory later in Life
News
HMOs, 3′SL, in pre-weaning Milk influences Attention, Learning and Memory later in Life
Related Resources >
Frequently Asked Questions
Frequently Asked Questions