Multiple Micronutrient Supplements in Pregnancy

In this episode of Milestones in Maternal Nutrition, Professor Andrew Prentice speaks with Dr. Klaus Kraemer about the development and the science behind UNIMMAP — the standardized multiple micronutrient supplement formulated for pregnant women in low- and middle-income countries. Dr. Kraemer explains how data from over 20 randomised trials and multiple meta-analyses demonstrate that multiple micronutrient supplements (MMS) reduces low birth weight by 12% and preterm birth by 8% compared to standard iron and folic acid, with even greater benefits — approaching 20% reduction in low birth weight and 30% in infant mortality — among underweight and anemic women. The discussion addresses UNIMMAP's formulation history, manufacturing complexity, cost-effectiveness, and the WHO's cautious conditional recommendation. Together, they examine the barriers that have slowed MMS adoption globally, and discuss what it will take to make this life-saving supplement the new standard of care for pregnant women everywhere.