Annales 76.3 Allergic or Pseudo-Allergic Gastrointestinal Disorders

Frank Ruemmele

The latest Annales Nestlé discusses epidemiology, clinical presentation, diagnosis, pathophysiology and treatment of inflammatory GI disorders, such as eosinophil GI diseases or allergic disorders including food protein-induced enterocolitis syndrome (FPIES) and food protein-induced allergic proctitis (FPIAP), as well as complex functional disorders, such as non-celiac gluten sensitivity (NCGS). The differentiation between lactose intolerance and cow’s milk allergy is also approached in this issue, which will help limit misunderstandings in diagnosing and managing these conditions.

Food avoidance or specific restriction diets to relief symptoms is currently very common action among patients, even without any diagnostic analyses, requiring attention from health care professionals. In the present series of 4 articles, this issue is addressed, raising the question of a link between food components and adverse reactions as true allergic reactions or mechanisms of food-induced intestinal complaints other than allergy, calling them “pseudo- allergic gastrointestinal disorders.