Annales Nestlé

This issue of Annales Nestlé highlights the fundamental importance of complementary feeding in shaping long-term health outcomes. Leading experts present evidence on how the timing, composition, and context of introducing solid foods influence risks for obesity and allergy, shape food preferences, and establish lifelong eating habits. The articles examine strategies for obesity prevention, harmonized global approaches to food allergy prevention, the biological and experiential factors that drive food acceptance, and optimal feeding practices for healthy growth. Together, these insights provide

This edition of Annales Nestlé highlights emerging research on the crucial role of breastfeeding and the gut microbiome during the first 1,000 days—a critical window for lifelong health. It explores how bioactive compounds in human milk shape the infant gut microbiome, influencing immunity, metabolism, neurodevelopment, and bone health. Delivery mode, diet, antibiotics, and environment significantly impact microbial colonization, with disruptions linked to increased risks of allergies, metabolic disorders, gastrointestinal diseases, and bone loss. Interventions for optimizing microbiome

Early childhood is a critical period when nutrition and environmental factors strongly influence lifelong brain development, physical health, and overall well-being. Both undernutrition and overnutrition can lead to growth faltering and increase the risk of non-communicable diseases (NCDs), with lasting effects on individual potential and broader societal outcomes. This issue of Annales Nestlé presents practical, up-to-date strategies for assessing growth and addressing both faltering and catch-up growth. It emphasizes early growth as a crucial phase for metabolic and developmental programming