The CoMiSS as a Predictor for the Diagnosis of Cow’s Milk Protein Allergy

Due to the lack of reliable diagnostic tests for cow’s milk protein allergy (CMPA), developing an awareness tool to recognize cow’s milk related symptoms for use by primary healthcare providers may help, as its name implies, in increasing the awareness and the recognition of cow’s milk related symptoms. A “Cow’s Milk-related Symptom Score” (CoMiSS), a score that considers general manifestations, dermatological, gastrointestinal and respiratory symptoms, was developed to be used as an awareness tool for cow’s milk related symptoms (1). Such a tool, helping in decision-making and management, will be appreciated by parents because it will avoid over- and under-diagnosis, and also shorten the duration of distress of the infants and parental anxiousness.