Growth and Metabolic Outcomes in Healthy Infants Fed Formulas with Age-Adapted Protein Concentrations from Birth Through 12 Months

ean-Charles Picaud, Mireille Castanet, Olivier Claris, Jean-Michel Hascoët, Catherine Gire, Frédéric Gottrand, Farid Boubred, Nicholas P. Hays, Jérôme Tanguy, Daniel Lepetit, Claude Billeaud

Human milk composition changes dynamically during lactation, whereas infant formula composition is relatively static. This may contribute to growth/metabolic differences between breastfed and formula-fed infants. The aim of this study was to evaluate growth and metabolic outcomes in healthy term infants fed sequential formulas with age-adapted protein concentrations from birth to 12 months, in comparison to breastfed infants. The new follow-on formula with age-adapted protein content, fed sequentially after standard starter formula, supports healthy growth comparable to WHO standards and body composition at 12 months similar to breastfed infants.