Why Do We Need Nutrition Therapy in an Era of Biologics? - David Wilson

The need for alternatives to chronic immunosuppression as the prime treatment strategy in IBD is vital. Patients and families are very concerned about drug safety. Despite undoubted impact, the efficacy of current and novel biologics is limited in inducing and maintaining remission, and there are safety issues with long-term use. Given that gut luminal content is influenced by diet and drives inflammation, the evidence for therapeutic benefit with dietary therapy, and patients’ strong interest in dietary strategies, it is vital to include diet as part of the therapeutic strategy for IBD.