Sialylated HMOs are Shaping the Development of Cognitive Functions

Human milk oligosaccharides (HMOs) are a key component of breast milk and have been proposed to be one of the mediators of breastfeeding beneficial effects on neurodevelopment and associated adult brain functions. Among the different types of HMOs, the sialylated HMOs are suggested to play a key role in brain development and functions. This study further confirms previous findings od pre clinical studies that absence of early life source of dietary sialylated HMOs lead to impaired cognitive functions, specifically attention, and spatial and working memory