Article

Interplay Between Estrogen and the Gut Microbiome Across Female Reproductive Transitions

Gut Microbiota
21 min read

Key messages:

  • Estrogen and the gut microbiome regulate each other: hormonal shifts directly influence gut composition, and the microbiome helps control circulating estrogen levels.
  • Each reproductive phase disrupts microbial balance differently: pregnancy, postpartum, and perimenopause cause distinct changes in gut flora that impact metabolism, inflammation, and mood.
  • Supporting the gut microbiome through targeted nutrition can ease hormonal symptoms: a diet rich in fiber, polyphenols, and fermented foods helps maintain microbial balance, optimize estrogen metabolism, and reduce inflammation during hormonal transitions.

Author(s): Francesco De Seta

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Francesco De Seta
Francesco De Seta

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