EAACI

European Academy of Allergy & Clinical Immunology

Food Allergy and Anaphylaxis Meeting and the European Consortium on Application of Flow Cytometry in Allergy (FAAM-EUROBAT) Digital 2020

Oct 16,2020 - Oct 17,2020

Human Milk Oligosaccharides: New Developments in the Management of Cow’s Milk Protein Allergy
 

Human milk oligosaccharides (HMO) are the third largest component in breastmilk. They resemble mucosal glycans at the host–microbe interface, supporting HMO to play important roles in orchestrating the host–microbial interactions via multiple mechanisms. These include preventing pathogen growth and adhesion, reducing inflammatory responses and aiding the mucosal barrier function, as well as promoting an early life microbiome. Observational studies with breastfed infants suggest that HMO  support the immune system with protection from infections and possibly allergies. It has been shown that feeding a formula with the two HMO, 2’FL and LNnT, reduces the risk for infections in both healthy and infants with cow’s milk protein allergy. Furthermore, feeding a formula with these two HMO supports a gut microbiota closer to breastfed infants. In this symposium we will learn more about the effect of HMO supplementation on the gut microbiome in children with cow’s milk protein allergy

European Academy of Allergy & Clinical Immunology (EAACI) Annual Congress 2019

Lisbon
Portugal
Jun 01,2019 - Jun 06,2019

Human Milk Oligosaccharides: New Ways to Shape the Gut Microbiome in Cow’s Milk Protein Allergy

The human gut is colonised by a wide diversity of microbes and they exhibit highly evolved synergistic relationships to provide essential biological functions to the host and how the gut microbiome is influenced by many factors in early life. It is important to establish a stable gut microbial community, which closely tracks host growth and immune development. The mechanisms whereby delays or alterations in the establishment of these communities can lead to microbiome immaturity, raise the risk of allergy development including cow’s milk protein allergy (CMPA).

Human milk oligosaccharides (HMO) are multifunctional breast milk components that shape the developing gut microbiota and influence the developing immune system. Supplementing specialty formulas for the management of CMPA with HMO offers a new way to shape the gut microbiome in infants with CMPA that for any reason cannot be breastfed.

 

European Academy of Allergy & Clinical Immunology (EAACI) Annual Congress 2014

Copenhagen, Denmark
Jun 07,2014 - Jun 11,2014

The Scientific Programme Committee carefully developed an outstanding programme under the theme: Challenging Dogmas. It covered the whole field of allergy, as well as lots of new topics and formats.