Focus: Cost-Effectiveness of Partially Hydrolyzed Whey Protein Formula in the Primary Prevention of Atopic Dermatitis in High-Risk Urban Infants in Southeast Asia
Proteins found in standard cow’s milk formula have been associated with an increased risk of atopic dermatitis, especially ininfants with a familial predisposition towards atopy. Compared to standard cow’s milk formula, partially or extensively hydrolyzedformulas are alternative protein sources that may reduce the risk of atopic dermatitis and other allergic disorders whenused in high-risk infants. This study compared the long-term (i.e. 6 years) economic impact of using a partially hydrolyzedwhey-based formula instead of a standard cow’s milk formula in the first 17 weeks of life in nonexclusively breastfed infantswho are at high risk of developing atopic dermatitis in Malaysia, Singapore, and the Philippines.The analysis was based on the 6-year results of the German Infant Nutritional Intervention (GINI) study, a large randomized clinical trial comparing the risk of atopic dermatitis in following feeding with standard cow’s milk formula versus partially hydrolyzed whey-based formula.