Breast milk may influence immune responses through its bioactive, immune-modulating components, such as Human milk oligosaccharides (HMOs), and / or through its positive impact on the development of intestinal microbiota. HMOs stimulate the development of a bifidogenic microbiome, which is boosting a maturation of the immune system resulting in a reduced risk of allergic disease. HMOs support the infants’ immune system through four potential mechanisms: supporting the growth of beneficial bacteria in the gut and eliminating pathogens, as well strengthening the gut barrier function and guiding a maturation on the immune system towards a balanced Th1/Th2 response. HMOs provide protection against allergy and infectious diseases directly through the interaction of the gut epithelial cells or indirectly through the modulation of the gut microbiota.
This is a video teaser with key points of the presentation of Prof. Yvan Vandenplas’ during the NNI online Satellite Symposia as scheduled for WCPGHAN 2020. Click in the link below if you want to see Prof. Yvan Vandenplas’ full talk: