Milk microbiome and neonatal colonization – Overview (videos)

Milk microbiome and neonatal colonization – Overview

Speakers:
Samuli Rautava

Summary

Breastfeeding confers the infant short and long-term health benefits and significantly modulates the developing infant gut microbiome. A specific human milk microbiome has relatively recently been discovered, but its origin remains poorly understood. Data from experimental and clinical studies suggest that the bacteria in milk may originate in the maternal gut and be transported via a specific enteromammary pathway the details of which have not been elucidated.

The milk microbiome is affected by maternal metabolic state, antibiotic use as well as the mode of delivery. Several clinical studies indicate that despite considerable differences in the overall composition of the milk and infant gut microbiomes, specific bacteria are detectable both in human milk and infant feces and that the bacteria in milk are a source of colonizing microbes to the neonatal gut.

If the microbes in human milk are discovered to contribute to the beneficial effects of breastfeeding, modulating or mimicking the milk microbiome may provide a novel means of improving child health.

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