Human Milk Microbiota: Origin and Potential Uses (videos)

Human Milk Microbiota: Origin and Potential Uses

Speakers:
Juan Rodriguez

Summary

At the beginning of the XXI century, microbiological studies on human milk started to describe the existence of its own microbiota. Hygienically collected milk samples from healthy women contain a relatively low bacterial load consisting mostly of Staphylocococcus, Streptococcus, and other Gram-positive bacteria (Corynebacterium, Propionibacterium, Lactobacillus and Bifidobacterium).

DNA from strict anaerobic bacteriais also detected in human milk samples. Colostrum and milk bacteria may play a key role in driving the development of the infant gut microbiota, the correct maturation of the infant immune system and the improvement of tolerance mechanisms. A well-balanced human milk microbiota is also relevant for maternal breast health.

Infant’s oral cavity and maternal skin may contaminate milk. Additionally, selected bacteria of the maternal digestive microbiota may access the mammary glands through oral- and entero-mammary pathways by involving mononuclear cells for their transport. These pathways would provide new opportunities for manipulating maternal-fetal microbiota, reducing the risk of preterm birth or infant diseases.

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