Educational Symposium supported by NNI on Microbiota and Bone, presented at European Calcified Tissue Society Congress (ECTS)
Bone is an organ that the gut has long been known to regulate through absorption of the key bone mineral, calcium. An increasing number of studies suggest that there are additional ways to regulate bone health, including gut the microbiome (GM). Studies have demonstrated that GM regulates postnatal skeleton development. Alterations in GM composition and host responses to the GM contribute to pathologic bone loss, while changes in GM composition that prevent, or reverse, bone loss may be achieved by nutritional supplements with pre-, pro-, and postbiotics. GM has emerged as critical regulator of the activity of bone regulating hormones.