Nestlé Research on Human Milk Oligosaccharides: Latest Update

Editor(s): .

Human Milk Oligosaccharides (HMOs), the third solid component of human milk, are complex structures with a high potential for specific functions. Research is revealing the full extent of the beneficial properties of HMOs. More than 200 HMOs have been detected so far and classified into three different categories: Fucosylated, Sialylated and Non-fucosylated neutral. This brochure presents the latest science by Nestlé Research on specific HMOs from these 3 categories in different benefit areas: brain development & cognition; gut comfort; protection against infections,  intestinal epithelial barrier, metabolic health and microbiome.


A Positive Correlation between Breast Milk 3’-Sialyllactose and Language Development during Early Infancy.

Author(s): Seoyoon Cho, Ziliang Zhu, Tengfei Li, Kristine Baluyot, Brittany Howell, Heather Hazlett, Jed Elison, Di Wu, Jian Yan, Weili Lin

A growing body of research, primarily through animal studies, has suggested that specific human milk oligosaccharides (HMOs), such as 2’-Fucosyllactose (2’FL), 3’-Sialyllactose (3’SL) and 6’-Sialyllactose (6’SL), may have a positive effect on neurodevelopment
and cognitive ability.