Annales 76.1 - Hot Topics in Nutrition – 75 Years Later

Editor(s): F. Haschke,. 76.1

The special issue of Annales Nestlé 76.1 is dedicated to celebrate 75 years of this international series, and explores topics which were burning decades ago and are still sensitive, with contributions from authors based in different parts of the world:

  • Prof. Andrew Prentice (The Gambia) outlines how “nutrition transition” in population of many low- and middle-income countries is triggering a new health challenge;
  • Prof. Hans van Goudoever (The Netherlands) performs a critical analysis of the crucial role of human milk in delivering adequate nutrition to support growth and health of preterm infants;
  • Dr. Ralf Heine (Switzerland) covers nutritional strategies for allergy prevention in the first year of life as well as new promisse and effective future treatment options;
  • Prof. Hania Szajewska (Poland) discusses the importance and influence of evidence-based medicine and clinical research on medical practice;
  • Prof. Jai K. Das  (Australia) and col. focus on nutritional requirements of older children, adolescents, and young women of childbearing age and the impact of the diet and nutritional status before and during pregnancy on the nutritional status, growth, and health of the offspring.

This edition of Annales Nestlé is a significant milestone in the history of pediatric medical communications. It is the 75th year in the international series that was originally launched in 1942, following on from an exclusively French-language version that first appeared in 1935. The contents of each issue of Annales Nestlé reflect the topics of interest and the state of the art and knowledge of the time, providing historical insights into the evolution of infant health and nutrition.  


The Double Burden of Malnutrition in Countries Passing through the Economic Transition

Author(s): A M. Prentice

In this paper Andrew Prentice outlines how, although many low- and middle-income countries (LMICs) are undergoing economic advancement, the accompanying “nutrition transition” occurring within their populations is triggering a new health challenge. Increasingly sedentary lifestyles and energy-dense diets have led to a rapid increase in the prevalence of overweight and obesity.

Improvements in nutrition in many LMICs have succeed in reducing rates of stunting, but in Africa, rapid population growth has led the absolute number of children suffering from stunting to rise. The populations of many parts of Africa, as of many other LMICs, are faced with the “double burden” of malnutrition, whereby under- and overnutrition are simultaneously present in the same population, and sometimes even in the same individual.

Nutrition for Preterm Infants: 75 Years of History

Author(s): J B. van Goudoever

Human milk plays a crucial role in delivering adequate nutrition to support growth and health for preterm infants during this vulnerable period of life. In this paper van Goudoever references the first article of Annales Nestlé published on the nutrition of neonates from 1983, placing his observations within the context of the history of modern preterm care. The development of human milk fortifiers, essential for meeting the high nutritional requirements of infants born prematurelly, and the improved methods for pasteurizing human donor milk are also discussed.

Evidence-Based Medicine and Clinical Research: Both Are Needed, Neither Is Perfect

Author(s): H. Szajewska

Although evidence-based medicine (EBM) had a positive influence on medical practice in the last quarter of the 20th century, it still needs further refinement, and that considerably more rigor is required in the design, execution, analysis of data from new sources – “big data” and “real-world data” – have the potential to bring about significant improvements in both EBM and clinical research, which are both to be transformed in the process. Strategies for the development of high-quality research have been developed, and if strictly adhered to by all stakeholders, this should lead to more valid and trustworthy findings.

Food Allergy Prevention and Treatment by Targeted Nutrition

Author(s): R. G. Heine

Giving the steadly rising prevalence of food allergies, food allergy prevention has become a global health priority. Breastfeeding is a key pillar of primary allergy prevention, and in recent years, reseach has encouraged the proactive introduction of hypoallergenic formulas in non-breastfed infants and of food allergens from the age of 4 months.

The article also assesses the transformations that have recently taken place in the treatment of food allergies, with immunotherapy via the oral or epicutaneous route offering the promise of effective future treatment strategies.