Probiotics can alter the composition of the intestinal microbiota and thus can modulate aspects of adaptive
and innate immunity in children. This has resulted in using probiotics to prevent, manage or treat various
health conditions such as diarrhoea, allergies, dental caries and gestational diabetes among other conditions.
However, the lack of uniform regulatory standards can open up avenues for marketing ineffective products
with false claims. Keeping all these in mind, there is an urgent need for a proper regulatory framework in India
to standardise the guidelines and regulations on the use of probiotics with international standards in order to
ensure their safe and effective use.
The Nestlé Nutrition Institute is extremely delighted to bring you review articles on probiotics. The article
“Probiotics and Immunity” reviews the development of the immune system in infants and children,
elaborates on the role of probiotics in the development of the gut microbiota and on aspects of the immune
system and finally, presents clinical data on the efficacy and benefits of probiotic supplementation, particularly
in infants, pregnant and lactating women. The article “Probiotics in Paediatrics: Functional, Safety
and Regulatory Aspects” provides an outline on the safety aspect of probiotics in different populations,
particularly infants and pregnant women. It also examines the regulatory framework that exists in India, USA
and neighboring countries.