Probiotics are live microorganisms which confer a health benefit to the host body. Thus, they are generally considered beneficial under certain situations. This particular issue of NNI Newsletter updates the readers about those areas where the probiotics have been observed to be beneficial to one’s health. Also, a more detailed explanation of the scientific study results about the impact of Probiotics on human health, their use during pregnancy and lactation period and the influence of probiotics on infants and children has been included. There are also a few case studies mentioned in this newsletter to exemplify the same benefits.