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Omega-3 may have benefits for dry AMD: Pilot Study

Posted:  Wednesday, November 06, 2013

Supplementation with EPA-rich omega-3 fatty acids could help battle inflammation in the macula and therefore improve the vision in patients with dry Age-related Macular Degeneration (AMD), according to the findings of a new pilot study.

Writing in PharmaNutrition , the research team report the findings from an open-label pilot study aimed at examining the potential for higher dose omega-3 fatty acids to provide clinical benefits to patients with dry AMD.

The team reported that supplemetation with the high-dose omega-3 fatty acids - providing 3.4 grams of eicosapentaenoic acid (EPA) and 1.6 g of docosahexaenoic acid (DHA) - led to significant improvements in vision acuity for 100% of participants within four and half months of supplementation commencing

Led by Tassos Georgiou from the Ophthalmos Research and Educational Institute, Cyprus, the team noted that AMD is the most common cause of severe and irreversible loss of central vision in people over the age of 50 - adding that there is no current approved treatment for dry AMD.

Since there is no existing treatment for dry AMD, the positive clinical improvements obtained in this pilot study should be considered striking since 100% of the patients had an increase of at least one line of vision within 4.5 months after starting the omega-3 fatty acid supplementation," said the authors.

Although the dose of omega-3 fatty acids used in these studies may appear high, in fact the average daily EPA and DHA dose used in the subjects reported was about one-third of those levels used in various prior studies in the treatment of severe brain trauma and ADHD," they added.

Tassos Georgiou, Anastasia Neokleous, Despina Nikolaou, Barry Sears, Pilot Study for Treating Dry Age-related Macular Degeneration (AMD) with High-Dose Omega-3 Fatty Acids, PharmaNutrition, Available online 18 October 2013

For study details:-Click Here!