The gastrointestinal tract hosts a huge quantity of microorganisms, mostly bacteria, which surpass in number our cells by 10 fold. In genetic terms, our gut microflora has 150 times our genes.
The criteria for infantile colic includes all of the following in infants from birth to 4 months of age: paroxysms of irritability, fussing or crying that start and stop without obvious cause; episodes lasting 3 or more hours per day and occurring at least 3 days per week for at least 1 week; and no failure to thrive.
GERD is a common disorder in infancy and childhood. The main patho-physiological cause is an inappropriate transient relaxation of the lower esophageal sphincter.