Infantile Colic: Novell Therapeutic Approach
Dr. Ramzi Kilani
Chief of Pediatrics and Neonatology at Farah and Istishari Hospitals - Amman
The classic Wessel definition of infantile colic also known as the “rule of three” is when an otherwise healthy infant cries inconsolably for more than three hours a day, more than three days a week for at least 3 weeks. Also, infantile colic is usually accompanied by painful facial expressions, flushing and a distended abdomen with flatulence. Although infantile colic is commonly reported and causes appreciable distress for parents and pediatricians, despite forty years of research, its etiology still remains unclear. Recently the role of intestinal microflora has growing importance. Studies suggest that alterations in the composition of the intestinal microflora appears to affect the immune response and gastrointestinal motility which may promote the onset of colic and other functional disorders such as regurgitation and functional constipation. A recent study shows that Lactobacillus reuteri improved colicky symptoms in colicky infants within one week of treatment compared to Simethicone, suggesting that probiotics may play a role in infantile colic (Savino et. al 2007). Modification of the intestinal microflora with the use of probiotics could represent a new therapeutic approach to infantile colic.