Renal Disease in Childhood

Editor(s): International Committee of Paediatricians Annales Nestlé Vol.61 / 1,  2003
  • Genetic Bases of Renal Diseases

    Author(s): C. Antignac

    Tremendous progress was made recently in the understanding of hereditary renal diseases through the identification of the genes and encoded proteins involved in many of the recognized disorders that has influenced diagnostic approaches substantially. These advances have been facilitated by the Human Genome Project, an international cooperative effort initiated in 1990, designed to elucidate the genome sequence of humans and selected experimental animal models. A draft of the human sequence that covers about 94% of our genome has been published in February 2001 [1] and the whole assembled sequence is nearly available.

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