Nutritional support has become a well established
component in patient care. Since its introduction
in the late sixties, total parenteral nutrition (TPN)
has enabled the survival of many patients and
reduced the incidence of malnutrition related to a
variety of digestive and non-digestive diseases.
The concept of parenteral nutrition began more
than three centuries ago when Sir Christopher
Wren was able to successfully infuse wine into the
veins of dogs. His work was succeeded by multiple
attempts by others to inject fat, milk and
other products subcutaneously and intravenously.
Since the first description of the successful use of
total parenteral nutrition (TPN) in an infant in
1944 , great progress has been made in the formulation
of energy sources and nutrients for use
Parenteral nutrition is the technique of providing
the body’s nutritional requirements intravenously.
The nutrients are water, glucose, electrolytes,
amino acids, lipids, vitamins, minerals and trace
metals. Home parenteral nutrition (HPN) is the
method of administering this support at home.
The advent of artificial nutrition is one of the major therapeutic advances of the last thirty years. Indeed,
continuous enteral nutrition and total parenteral nutrition (TPN) have reversed the prognosis for illnesses
which were fatal hitherto.