Allergies are one of the most prevalent non communicable diseases, and most of them generate impairment in quality of life and huge direct and indirect costs. Food allergy and atopic dermatitis are also increasing their prevalence and affecting infants in their first months of life. In an attempt to diminish its burden, strategies in prevention have been discussed. As these diseases result from genetics and variety of environmental factors, it is important to understand this interaction and define which factors should be avoided or what changes in diet or lifestyle should be proposed. Prevention allergy strategies are the most powerful weapon against the burden of allergic diseases.